Our team of professionals are trained to conduct clinical trials for people who want to quit smoking.
Our trials test medications, behavioral approaches and various combinations of both in an attempt to find the most effective smoking cessation treatment. Our staff is also trained to conduct behavioral counseling.
The Embera Study
The purpose of the Embera study is to see if using a combination of two medications may help you quit smoking. Both medications (metyrapone and oxazepam) are Food and Drug Administration (FDA) approved, but not specifically to help people quit smoking. Metyrapone is a drug used to test hypothalamic-pituitary ACTH function and oxazepam is a drug used to treat anxiety or alcohol withdrawal symptoms. The use of these drugs together is investigational and has not been approved by the FDA.
- Between 21-65 years old and able to pass a urine drug screening.
- Smokes at least 10 cigarettes per day.
- Are not currently diagnosed with any serious medical or psychological conditions.
- Have not used any electronic cigarettes, vapes, chewing tobacco, cigars, pipes, hookahs, or nicotine replacement therapy (nicotine patches, lozenges, gum, etc.) in the last 2 weeks.
- Because these two drugs are not FDA approved to be used together, females must be unable to become pregnant during the course of this study. This means women must be post-menopausal or surgically sterile.
- Must not have recently used any of the following: illegal drugs, investigation drugs, SSRIs, antidepressants, antipsychotics, opiates, biotin products, glucocorticoids (oral, inhaled, or topical), or joint injections.
The COCO Study
The main purpose of this research study is to compare the measured amount of carbon monoxide (CO) in your exhaled breath between two different CO monitors and compare these to the amount of carbon monoxide in your blood measured directly from a sample of blood from your vein. Both of the CO monitors being used in this study are approved by the United States Food and Drug Administration (FDA). Another purpose of this research study is to evaluate a new mobile app called eResearch. This app was developed by Rose Research Center to conduct remote research. .
- Between 21-65 years old
- Able to pass a urine drug screen
- Daily cigarette smoker
- Willing to use reduced nicotine cigarettes and an e-cigarette, both provided by Rose Research
- No intention of quitting smoking in the next 30 days.
- Must not have recently used any of the following: illegal drugs, investigational drugs, or chronic opioid use.
The CAST Study
The purpose of this research study is to see if an investigational drug, called centanafadine can help you quit smoking cigarettes. An investigational drug is a drug that is being studied before approval by the United States Food and Drug Administration (FDA).
- Between 21-65 years old
- Desire to quit smoking cigarettes
- Willingness to take study medications as directed
- Currently smoke 10 or more cigarettes per day
- Able to pass a urine drug test
- No current serious medical conditions
- No use of other tobacco products in the last 14 days (including cigars, pipes, hookahs, e-cigarettes, or nicotine replacement therapy.)
For Future Studies
Fill out our form below for more information
Participant information is maintained in a volunteer database system and retained for future studies as they become available. Pertinent information is confidentially kept on file to aid in selecting highly qualified candidates for research studies.
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