Our team of professionals are trained to conduct clinical trials for people who want to quit smoking.
Our trials test medications, behavioral approaches and various combinations of both in an attempt to find the most effective smoking cessation treatment. Our staff is also trained to conduct behavioral counseling.
The BuZonE RCT Study
The main purpose of this research study is to see if taking a combination of zonisamide and bupropion for a short time helps you switch to using only an e-cigarette. Zonisamide is a drug approved by the United States Food and Drug Administration (FDA) for treatment of seizures. Bupropion (also known as Zyban) is a drug approved by the FDA for use as an aid to quit smoking (but not for switching from combustible cigarettes to e-cigarettes). The use of the combination of zonisamide and bupropion is not FDA approved for the purpose of switching from combustible cigarettes to e-cigarette use and is therefore considered investigational for this study.
BuZonE RCT FAQ
- Between 21-65 years old
- Desire to switch to an e-cigarette
- Willingness to take study medications as directed
- Currently smoke 10 or more cigarettes per day
- Able to pass a urine drug test
- No current serious medical conditions
- No use of other tobacco products in the last 14 days
JUMP FAQ
- Between 22-65 years old
- Willing to try menthol flavored e-cigarettes
- Currently smokes commercially available combustible cigarettes per day
- No known allergies or sensitivities to any ingredients found in tobacco or e-cigarette products or any of the components in e-liquids (nicotine, flavor, benzoic acid, propylene glycol and glycerol, menthol, peppermint oil)
- No current serious medical conditions
- Able to read, understand, and willing to sign an informed consent form (ICF) and complete questionnaires written in English
- Not pregnant, breastfeeding, or planning to become pregnant
- Participants will receive $25 for completing screening procedures at Study Visit 1. After all screening procedures, if participants are eligible to continue in the study, they will try the first product and will receive an additional $75. Participants will also receive $25 at this visit to cover the cost of gas price increases.
- Following completion of each product-use session (Visit 2 through Visit 6) participants will receive $75 and an additional payment of $25 to cover the cost of gas price increases ($100 total per visit).
- Participants who complete all product-use sessions will be eligible for a one-time payment of $200 that will be paid at the completion of all procedures at Visit 6.
The JUMP Study
The purpose of this research study is to have you try and rate the current and new menthol flavors of one brand, two other menthol-flavored e-cigarettes, and your usual brand of combustible cigarettes. You will use one of each of these products for 20 minutes (one at each study visit). After the 20-minute product-use time, you will complete questionnaires based on the experience.
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For Future Studies
Fill out our form below for more information
Participant information is maintained in a volunteer database system and retained for future studies as they become available. Pertinent information is confidentially kept on file to aid in selecting highly qualified candidates for research studies.
Why should I participate?
Participants may gain access to new research treatments before they are widely available.
Additionally, participants are compensated for their time and receive study-related products and medications at no cost. You may be among the first to benefit if the approach being studied is found to be helpful.
